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  "Title": "Simulation-Based Calculation of Basket Trial Operating\nCharacteristics",
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  "Authors@R": "c(\nperson(\"Lukas\", \"Baumann\", , \"baumann@imbi.uni-heidelberg.de\",\nrole = c(\"aut\", \"cre\"),\ncomment = c(ORCID = \"0000-0001-7931-7470\")),\nperson(\"Lukas D\", \"Sauer\", ,\"sauer@imbi.uni-heidelberg.de\",\nrole = c(\"aut\"),\ncomment = c(ORCID = \"0000-0002-1340-9994\")),\nperson(\"Sabrina\", \"Schmitt\", ,\"sabrina.schmitt@uni-wuerzburg.de\",\nrole = c(\"aut\"),\ncomment = c(ORCID = \"0009-0008-2719-6513\"))\n)",
  "Description": "Provides a unified syntax for the simulation-based\ncomparison of different single-stage basket trial designs with\na binary endpoint and equal sample sizes in all baskets.\nMethods include the designs by Baumann et al. (2025)\n<doi:10.1080/19466315.2024.2402275>, Schmitt and Baumann (2025)\n<doi:10.1080/19466315.2025.2486231>, Fujikawa et al. (2020)\n<doi:10.1002/bimj.201800404>, Berry et al. (2020)\n<doi:10.1177/1740774513497539>, and Neuenschwander et al.\n(2016) <doi:10.1002/pst.1730>. For the latter two designs, the\nfunctions are mostly wrappers for functions provided by the\npackage 'bhmbasket'.",
  "License": "GPL (>= 3)",
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  "Date/Publication": "2026-05-22 14:37:42 UTC",
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  "Author": "Lukas Baumann [aut, cre] (ORCID:\n<https://orcid.org/0000-0001-7931-7470>),\nLukas D Sauer [aut] (ORCID: <https://orcid.org/0000-0002-1340-9994>),\nSabrina Schmitt [aut] (ORCID: <https://orcid.org/0009-0008-2719-6513>)",
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  "_created": "2026-05-22T16:36:35.000Z",
  "_published": "2026-05-22T16:44:08.794Z",
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    "geom_prior",
    "get_data",
    "get_details",
    "get_evaluation",
    "get_results",
    "get_scenarios",
    "opt_design",
    "setup_app",
    "setup_bhm",
    "setup_binomial",
    "setup_cpp",
    "setup_cppglobal",
    "setup_cpplim",
    "setup_exnex",
    "setup_fujikawa",
    "setup_jsdglobal",
    "setup_mml",
    "setup_mmlglobal",
    "toer"
  ],
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    {
      "page": "adjust_lambda",
      "title": "Adjust Lambda",
      "topics": [
        "adjust_lambda"
      ]
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      "page": "adjust_lambda.bhm",
      "title": "Adjust Lambda for the BHM Design",
      "topics": [
        "adjust_lambda.bhm"
      ]
    },
    {
      "page": "adjust_lambda.default",
      "title": "Adjust Lambda",
      "topics": [
        "adjust_lambda.default"
      ]
    },
    {
      "page": "adjust_lambda.exnex",
      "title": "Adjust Lambda for the EXNEX Design",
      "topics": [
        "adjust_lambda.exnex"
      ]
    },
    {
      "page": "ecd",
      "title": "Calculate the Expected Number of Correct Decisions for a Basket Trial Design",
      "topics": [
        "ecd"
      ]
    },
    {
      "page": "geom_borrow",
      "title": "Plot a Bayesian basket trial's posterior distribution after borrowing",
      "topics": [
        "geom_borrow"
      ]
    },
    {
      "page": "geom_borrow.fujikawa",
      "title": "Plot a Fujikawa basket trial's posterior distribution after borrowing",
      "topics": [
        "geom_borrow.fujikawa"
      ]
    },
    {
      "page": "geom_posterior",
      "title": "Plot a Bayesian basket trial's posterior distribution",
      "topics": [
        "geom_posterior"
      ]
    },
    {
      "page": "geom_posterior.fujikawa",
      "title": "Plot a Fujikawa basket trial's posterior distribution",
      "topics": [
        "geom_posterior.fujikawa"
      ]
    },
    {
      "page": "geom_prior",
      "title": "Plot a Bayesian basket trial's prior distribution",
      "topics": [
        "geom_prior"
      ]
    },
    {
      "page": "geom_prior.fujikawa",
      "title": "Plot a Fujikawa basket trial's prior distribution",
      "topics": [
        "geom_prior.fujikawa"
      ]
    },
    {
      "page": "get_data",
      "title": "Simulate Data Based on a Binomial Distribution",
      "topics": [
        "get_data"
      ]
    },
    {
      "page": "get_details",
      "title": "Get Details of a Basket Trial Simulation",
      "topics": [
        "get_details"
      ]
    },
    {
      "page": "get_details.app",
      "title": "Get Details of a Basket Trial Simulation with the Adaptive Power Prior Design for sequential clinical trials",
      "topics": [
        "get_details.app"
      ]
    },
    {
      "page": "get_details.bhm",
      "title": "Get Details of a BHM Basket Trial Simulation",
      "topics": [
        "get_details.bhm"
      ]
    },
    {
      "page": "get_details.binomial",
      "title": "Get Details of a Basket Trial with the Frequentist Binomial Design",
      "topics": [
        "get_details.binomial"
      ]
    },
    {
      "page": "get_details.cpp",
      "title": "Get Details of a Basket Trial Simulation with the Calibrated Power Prior Design",
      "topics": [
        "get_details.cpp"
      ]
    },
    {
      "page": "get_details.cppglobal",
      "title": "Get Details of a Basket Trial Simulation with the Global Calibrated Power Prior Design",
      "topics": [
        "get_details.cppglobal"
      ]
    },
    {
      "page": "get_details.cpplim",
      "title": "Get Details of a Basket Trial Simulation with the Limited Calibrated Power Prior Design",
      "topics": [
        "get_details.cpplim"
      ]
    },
    {
      "page": "get_details.exnex",
      "title": "Get Details of a Basket Trial Simulation with the EXNEX Design",
      "topics": [
        "get_details.exnex"
      ]
    },
    {
      "page": "get_details.fujikawa",
      "title": "Get Details of a Basket Trial Simulation with Fujikawa's Design",
      "topics": [
        "get_details.fujikawa"
      ]
    },
    {
      "page": "get_details.jsdglobal",
      "title": "Get Details of a Basket Trial Simulation with the Power Prior Design Based on Global JSD Weights",
      "topics": [
        "get_details.jsdglobal"
      ]
    },
    {
      "page": "get_details.mml",
      "title": "Get Details of a Basket Trial Simulation with the MML Design",
      "topics": [
        "get_details.mml"
      ]
    },
    {
      "page": "get_details.mmlglobal",
      "title": "Get Details of a Basket Trial Simulation with the Global MML Design",
      "topics": [
        "get_details.mmlglobal"
      ]
    },
    {
      "page": "get_evaluation",
      "title": "Evaluate a Basket Trial",
      "topics": [
        "get_evaluation"
      ]
    },
    {
      "page": "get_evaluation.app",
      "title": "Evaluate a Basket Trial with the Adaptive Power Prior Design for sequential clinical trials",
      "topics": [
        "get_evaluation.app"
      ]
    },
    {
      "page": "get_evaluation.bhm",
      "title": "Evaluate a BHM Basket Trial",
      "topics": [
        "get_evaluation.bhm"
      ]
    },
    {
      "page": "get_evaluation.cpp",
      "title": "Evaluate a Basket Trial with the Calibrated Power Prior Design",
      "topics": [
        "get_evaluation.cpp"
      ]
    },
    {
      "page": "get_evaluation.cpplim",
      "title": "Evaluate a Basket Trial with the Limited Calibrated Power Prior Design",
      "topics": [
        "get_evaluation.cpplim"
      ]
    },
    {
      "page": "get_evaluation.exnex",
      "title": "Evaluate a Basket Trial with the EXNEX Design",
      "topics": [
        "get_evaluation.exnex"
      ]
    },
    {
      "page": "get_evaluation.fujikawa",
      "title": "Evaluate a Basket Trial with Fujikawa's Design",
      "topics": [
        "get_evaluation.fujikawa"
      ]
    },
    {
      "page": "get_results",
      "title": "Get Results for Simulation of Basket Trial Designs",
      "topics": [
        "get_results"
      ]
    },
    {
      "page": "get_results.app",
      "title": "Get Results for Simulation of a Basket Trial with Adaptive Power Prior Design",
      "topics": [
        "get_results.app"
      ]
    },
    {
      "page": "get_results.bhm",
      "title": "Get Results for Simulation of a Basket Trial with the BHM Design",
      "topics": [
        "get_results.bhm"
      ]
    },
    {
      "page": "get_results.cpp",
      "title": "Get Results for Simulation of a Basket Trial with a Calibrated Power Prior Design",
      "topics": [
        "get_results.cpp"
      ]
    },
    {
      "page": "get_results.cppglobal",
      "title": "Get Results for Simulation of a Basket Trial with a Global Calibrated Power Prior Design",
      "topics": [
        "get_results.cppglobal"
      ]
    },
    {
      "page": "get_results.cpplim",
      "title": "Get Results for Simulation of a Basket Trial with a Limited Calibrated Power Prior Design",
      "topics": [
        "get_results.cpplim"
      ]
    },
    {
      "page": "get_results.exnex",
      "title": "Get Results for Simulation of a Basket Trial with the EXNEX Design",
      "topics": [
        "get_results.exnex"
      ]
    },
    {
      "page": "get_results.fujikawa",
      "title": "Get Results for Simulation of a Basket Trial with Fujikawa's Design",
      "topics": [
        "get_results.fujikawa"
      ]
    },
    {
      "page": "get_results.jsdglobal",
      "title": "Get Results for Simulation of a Basket Trial with the Power Prior Design Based on Global JSD Weights",
      "topics": [
        "get_results.jsdglobal"
      ]
    },
    {
      "page": "get_results.mml",
      "title": "Get Results for Simulation of a Basket Trial with the MML Design",
      "topics": [
        "get_results.mml"
      ]
    },
    {
      "page": "get_results.mmlglobal",
      "title": "Get Results for Simulation of a Basket Trial with the Global MML Design",
      "topics": [
        "get_results.mmlglobal"
      ]
    },
    {
      "page": "get_scenarios",
      "title": "Create a Scenario Matrix",
      "topics": [
        "get_scenarios"
      ]
    },
    {
      "page": "opt_design",
      "title": "Optimize a Basket Trial Design",
      "topics": [
        "opt_design"
      ]
    },
    {
      "page": "setup_app",
      "title": "Set Up Adaptive Power Prior Design Object",
      "topics": [
        "setup_app"
      ]
    },
    {
      "page": "setup_bhm",
      "title": "Set Up BHM Design Object",
      "topics": [
        "setup_bhm"
      ]
    },
    {
      "page": "setup_binomial",
      "title": "Set Up Frequentist Binomial Design Object",
      "topics": [
        "setup_binomial"
      ]
    },
    {
      "page": "setup_cpp",
      "title": "Set Up Calibrated Power Prior Design Object",
      "topics": [
        "setup_cpp"
      ]
    },
    {
      "page": "setup_cppglobal",
      "title": "Set Up Global Calibrated Power Prior Design Object",
      "topics": [
        "setup_cppglobal"
      ]
    },
    {
      "page": "setup_cpplim",
      "title": "Set Up Limited Calibrated Power Prior Design Object",
      "topics": [
        "setup_cpplim"
      ]
    },
    {
      "page": "setup_exnex",
      "title": "Set Up EXNEX Design Object",
      "topics": [
        "setup_exnex"
      ]
    },
    {
      "page": "setup_fujikawa",
      "title": "Set Up Fujikawa Design Object",
      "topics": [
        "setup_fujikawa"
      ]
    },
    {
      "page": "setup_jsdglobal",
      "title": "Set Up Global JSD Design Object",
      "topics": [
        "setup_jsdglobal"
      ]
    },
    {
      "page": "setup_mml",
      "title": "Set Up mml Design Object",
      "topics": [
        "setup_mml"
      ]
    },
    {
      "page": "setup_mmlglobal",
      "title": "Set Up mmlglobal Design Object",
      "topics": [
        "setup_mmlglobal"
      ]
    },
    {
      "page": "toer",
      "title": "Calculate the Type 1 Error Rate for a Basket Trial Design",
      "topics": [
        "toer"
      ]
    }
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